Aplagon Announces EUR 7 Million Financing to Advance its APAC Therapeutic for Thrombo-Inflammatory Diseases into Phase 2A Clinical Trials

Financing led by new Investors Fåhraeus Startup and Growth and EIC Fund HELSINKI, 3rd February 2025. Aplagon, a clinical stage biopharmaceutical company developing a first-in-class therapeutic for thrombo-inflammatory diseases, known as APAC, a heparin proteoglycan mimetic with antiplatelet and anticoagulant effects, announced today it has closed a EUR 7 million financing. The funding round was […]

First Patient Dosed in the CHASE Clinical Trial for Aplagon’s APAC Therapeutic for Thrombo-Inflammatory Diseases

Company’s heparin proteoglycan mimetic now in three clinical trials HELSINKI, October 24, 2024.  Aplagon Oy (Aplagon), a clinical stage biopharmaceutical company developing a first-in-class therapeutic (APAC, a heparin proteoglycan mimetic) for thrombo-inflammatory diseases, announced today the first patient had been administered radiolabeled APAC and all three positron emission tomography / computed tomography (PET/CT) imaging sessions […]

Aplagon Signed EIC-Accelerator Grant Agreement

HELSINKI, November 16, 2022. Aplagon Oy (Aplagon), the Finnish pharmaceutical development company developing first-in-class vasculoprotective antithrombotic agents (APACs) to treat vascular injury related blood vessel occlusions and tissue damage, today announced that it had signed an EIC Accelerator grant agreement (Grant Agreement) with the European Innovation Council and SMEs Executive Agency (EISMEA). Under the Grant […]

Aplagon Joins The TRACER Excellence Program to Perform In-Human Imaging Study

HELSINKI, FINLAND and GRONINGEN, THE NETHERLANDS, September 8, 2022. Today, Aplagon Oy (“Aplagon”) announced that it will start its in-human imaging study to visualize the effect of its innovative APAC compound in patients with peripheral arterial occlusive disease / critical limb ischemia. The study will be executed in collaboration with TRACER B.V. (“TRACER”), a CRO […]

First Patient Treated in First Clinical Study for Aplagon’s APAC

HELSINKI, June 7, 2022. Aplagon Oy (“Aplagon”), the Finnish pharmaceutical development company developing first-in-class vasculoprotective antithrombotic agents to treat vascular injury related blood vessel occlusions and tissue damage, today announced that its lead pharmaceutical agent, APAC, has been administered for the first time in a clinical study. The Phase 1 clinical study is primarily intended […]

Aplagon Publishes New Data in Prestigious Journal of Cardiovascular Pharmacology

HELSINKI, September 1, 2021. Aplagon Oy (“Aplagon”), the Finnish pharmaceutical development company developing first-in-class vasculoprotective antithrombotic compounds to treat vascular injury related blood vessel occlusions and tissue damage, today announced the publication of new data as well as an accompanying commentary by third-party experts in the leading, peer-reviewed Journal of Cardiovascular Pharmacology. The article, “Safety […]

Aplagon Closes Oversubscribed EUR 2.2M Funding Round

HELSINKI, May 28, 2021. Aplagon Oy (“Aplagon”), the Finnish pharmaceutical development company developing first-in-class vasculoprotective antithrombotic compounds to treat vascular injury related blood vessel occlusions and tissue damage, today announced the closing of a EUR 2.2 million funding round. The fundraise was arranged in collaboration with Invesdor Group and was oversubscribed. These funds increase the […]

Aplagon Partners with Cadila Pharmaceuticals to Develop and Commercialize APAC First-in-Class Antithrombotics for the Prevention of Blood Vessel Occlusions Related to Vascular Interventions

HELSINKI AND STOCKHOLM, September 19, 2017. Aplagon Oy (“Aplagon”) and Cadila Pharmaceuticals Sweden AB today announced a development and commercialization agreement for Aplagon’s lead APAC product. APACs are proprietary, locally acting, potent antithrombotic products, which target blood vessel wall injury. Under the agreement, Cadila Pharmaceuticals Sweden AB together with its parent company Cadila Pharmaceuticals Limited, […]